Expression of OR2T1 in cancer - Summary

CANCER ATLAS

Gene description

Olfactory receptor, family 2, subfamily T, member 1

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

No evidence

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA063064

GENE INFORMATION
Gene name	OR2T1 (HGNC Symbol)
Synonyms	OR1-25
Description	Olfactory receptor, family 2, subfamily T, member 1 (HGNC Symbol)
Entrez gene summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	q44
Chromosome location (bp)	248405995 - 248407104
Protein evidence	No evidence (all genes)
Ensembl	ENSG00000175143 (version 83.38)
Entrez gene	26696
UniProt	O43869 (UniProt - Inferred from homology)
neXtProt	NX_O43869
Antibodypedia	OR2T1 antibodies

PROTEIN BROWSER

OR2T1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OR2T1-001 ENSP00000355430 ENST00000366474	O43869 [Direct mapping] Olfactory receptor 2T1 Show all	G-protein coupled receptors Odorant/olfactory and gustatory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004984 [olfactory receptor activity] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007608 [sensory perception of smell] GO:0016021 [integral component of membrane] GO:0050911 [detection of chemical stimulus involved in sensory perception of smell] Show all	369 aa 42 kDa	No	8