Cell atlas - GOLGA8A - The Human Protein Atlas

GENERAL INFORMATION
Gene name	GOLGA8A
Gene description	Golgin A8 family, member A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the Golgi apparatus. In addition localized to the cytosol. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Mixed
Protein evidence	Evidence at transcript level
Main location	Localized to the Golgi apparatus (approved)
Additional location	In addition localized to the Cytosol (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA051808
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the Golgi apparatus. In addition localized to the cytosol. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Golgi apparatus (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location	Single-cell variation
HPA051808	HEK 293	Golgi apparatus
HPA051808	HEK 293	Cytosol
HPA051808	HeLa	Golgi apparatus	Intensity
HPA051808	U-2 OS	Golgi apparatus
HPA051808	U-2 OS	Cytosol

GENE INFORMATION
Gene name	GOLGA8A (HGNC Symbol)
Synonyms	GM88, GOLGIN-67
Description	Golgin A8 family, member A (HGNC Symbol)
Entrez gene summary	The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked, flattened membrane sacs referred to as cisternae. Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The golgins constitute a family of proteins which are localized to the Golgi. This gene encodes a golgin which structurally resembles its family member GOLGA2, suggesting that they may share a similar function. There are many similar copies of this gene on chromosome 15. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
Chromosome	15
Cytoband	q14
Chromosome location (bp)	34379068 - 34437466
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000175265 (version 83.38)
Entrez gene	23015
UniProt	A7E2F4 (UniProt - Evidence at transcript level)
neXtProt	NX_A7E2F4
Antibodypedia	GOLGA8A antibodies

PROTEIN BROWSER

GOLGA8A-001	GOLGA8A-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GOLGA8A-001 ENSP00000352111 ENST00000359187	A7E2F4 [Direct mapping] Golgin subfamily A member 8A Show all	Predicted intracellular proteins Show all	GO:0005794 [Golgi apparatus] GO:0032580 [Golgi cisterna membrane] Show all	603 aa 67.3 kDa	No	0
GOLGA8A-201 ENSP00000402791 ENST00000432566	A7E2F4 [Direct mapping] Golgin subfamily A member 8A Show all	Predicted intracellular proteins Show all	GO:0005794 [Golgi apparatus] GO:0032580 [Golgi cisterna membrane] Show all	631 aa 70.1 kDa	No	0