Expression of LONRF3 in cancer - Summary

CANCER ATLAS

Gene description

LON peptidase N-terminal domain and ring finger 3

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA050422

GENE INFORMATION
Gene name	LONRF3 (HGNC Symbol)
Synonyms	FLJ22612, RNF127
Description	LON peptidase N-terminal domain and ring finger 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Multiple alternatively spliced transcript variants have been suggested, but their full length natures are not clear. [provided by RefSeq, Jul 2008]
Chromosome	X
Cytoband	q24
Chromosome location (bp)	118974614 - 119018355
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000175556 (version 83.38)
Entrez gene	79836
UniProt	Q496Y0 (UniProt - Evidence at protein level)
neXtProt	NX_Q496Y0
Antibodypedia	LONRF3 antibodies

PROTEIN BROWSER

LONRF3-002	LONRF3-005	LONRF3-201	LONRF3-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LONRF3-002 ENSP00000414519 ENST00000439603	H0Y7Q8 [Direct mapping] LON peptidase N-terminal domain and RING finger protein 3 Show all	Predicted intracellular proteins Show all	GO:0004176 [ATP-dependent peptidase activity] GO:0005515 [protein binding] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	525 aa 59.3 kDa	No	0
LONRF3-005 ENSP00000360690 ENST00000371628	Q496Y0 [Direct mapping] LON peptidase N-terminal domain and RING finger protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004176 [ATP-dependent peptidase activity] GO:0005515 [protein binding] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	759 aa 84.5 kDa	No	0
LONRF3-201 ENSP00000307732 ENST00000304778	Q496Y0 [Direct mapping] LON peptidase N-terminal domain and RING finger protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004176 [ATP-dependent peptidase activity] GO:0005515 [protein binding] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	718 aa 79.8 kDa	No	0
LONRF3-202 ENSP00000408894 ENST00000422289	B3KUN7 [Direct mapping] LON peptidase N-terminal domain and RING finger protein 3; LON peptidase N-terminal domain and ring finger 3, isoform CRA_b; cDNA FLJ40322 fis, clone TESTI2030917, highly similar to Homo sapiens LON peptidase N-terminal domain and ring finger 3 (LONRF3), transcript variant 1, mRNA Show all	Predicted intracellular proteins Show all	GO:0004176 [ATP-dependent peptidase activity] GO:0005515 [protein binding] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	503 aa 57.1 kDa	No	0