Cell atlas - ARL4D - The Human Protein Atlas

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ARL4D

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus
	Vesicles

Human cell
	Golgi Apparatus
	Vesicles

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GENERAL INFORMATION
Gene name	ARL4D
Gene description	ADP-ribosylation factor-like 4D
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to vesicles. In addition localized to the Golgi apparatus.
RNA cell category	Cell line enhanced (hTCEpi)
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved)
Additional location	In addition localized to the Golgi apparatus (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA060379
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (hTCEpi) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to vesicles. In addition localized to the Golgi apparatus.

Main location

Vesicles (approved)

Additional location

Golgi apparatus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA060379	Hep G2	Golgi apparatus
	HPA060379	SiHa	Vesicles
	HPA060379	U-2 OS	Vesicles

GENE INFORMATION
Gene name	ARL4D (HGNC Symbol)
Synonyms	ARF4L
Description	ADP-ribosylation factor-like 4D (HGNC Symbol)
Entrez gene summary	ADP-ribosylation factor 4D is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4D is closely similar to ARL4A and ARL4C and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in membrane-associated intracellular trafficking. Mutations in this gene have been associated with Bardet-Biedl syndrome (BBS). [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q21.31
Chromosome location (bp)	43398959 - 43401137
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000175906 (version 83.38)
Entrez gene	379
UniProt	P49703 (UniProt - Evidence at protein level)
neXtProt	NX_P49703
Antibodypedia	ARL4D antibodies

PROTEIN BROWSER

ARL4D-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARL4D-001 ENSP00000322628 ENST00000320033	P49703 [Direct mapping] ADP-ribosylation factor-like protein 4D Show all	Predicted intracellular proteins Show all	GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0009306 [protein secretion] GO:0015031 [protein transport] GO:0016020 [membrane] Show all	201 aa 22.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.