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Most malignant cells displayed weak to moderate nuclear positivity. Glioma, urothelial and a few endometrial cancers expressed strong staining. Several cases of liver, renal, stomach and pancreatic cancers were negative.
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007411 [axon guidance] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007411 [axon guidance] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007411 [axon guidance] GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007411 [axon guidance] GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007411 [axon guidance] GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007411 [axon guidance] GO:0045892 [negative regulation of transcription, DNA-templated]
A0A0A0MT21 [Direct mapping] Zinc finger protein 683
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Predicted intracellular proteins
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007411 [axon guidance] GO:0045892 [negative regulation of transcription, DNA-templated]
A0A0A0MSJ7 [Direct mapping] Zinc finger protein 683
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Predicted intracellular proteins
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007411 [axon guidance] GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0001779 [natural killer cell differentiation] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007411 [axon guidance] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding]