Expression of FAM89B in cancer - Summary

CANCER ATLAS

Gene description

Family with sequence similarity 89, member B

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA046895

GENE INFORMATION
Gene name	FAM89B
Synonyms
Description	Family with sequence similarity 89, member B (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q13.1
Chromosome location (bp)	65572349 - 65574198
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000176973 (version 83.38)
Entrez gene	23625
UniProt	Q8N5H3 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N5H3
Antibodypedia	FAM89B antibodies

PROTEIN BROWSER

FAM89B-001	FAM89B-002	FAM89B-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM89B-001 ENSP00000314829 ENST00000316409	Q8N5H3 [Direct mapping] Protein FAM89B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001222 [transcription corepressor binding] GO:0005737 [cytoplasm] GO:0009986 [cell surface] GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] GO:0060392 [negative regulation of SMAD protein import into nucleus] Show all	176 aa 18.7 kDa	No	0
FAM89B-002 ENSP00000402439 ENST00000449319	Q8N5H3 [Direct mapping] Protein FAM89B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001222 [transcription corepressor binding] GO:0005737 [cytoplasm] GO:0009986 [cell surface] GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] GO:0060392 [negative regulation of SMAD protein import into nucleus] Show all	154 aa 15.4 kDa	No	0
FAM89B-004 ENSP00000431459 ENST00000530349	Q8N5H3 [Direct mapping] Protein FAM89B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001222 [transcription corepressor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0009986 [cell surface] GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] GO:0060392 [negative regulation of SMAD protein import into nucleus] Show all	189 aa 20.1 kDa	No	0