Tissue expression of PDDC1 - Summary - The Human Protein Atlas

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PDDC1

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	PDDC1
Gene description	Parkinson disease 7 domain containing 1
Protein class	Enzymes Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in all tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA008812
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	PDDC1 (HGNC Symbol)
Synonyms	FLJ34283
Description	Parkinson disease 7 domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	p15.5
Chromosome location (bp)	767220 - 777488
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177225 (version 83.38)
Entrez gene	347862
UniProt	Q8NB37 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NB37
Antibodypedia	PDDC1 antibodies

PROTEIN BROWSER

PDDC1-003	PDDC1-006	PDDC1-010	PDDC1-012	PDDC1-014	PDDC1-016	PDDC1-017

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PDDC1-003 ENSP00000321691 ENST00000319863	Q8NB37 [Direct mapping] Parkinson disease 7 domain-containing protein 1 Show all	Enzymes Peptidases Cysteine-type peptidases Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0019172 [glyoxalase III activity] GO:0019243 [methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione] GO:0019249 [lactate biosynthetic process] GO:0070062 [extracellular exosome] Show all	220 aa 23.3 kDa	Yes	0
PDDC1-006 ENSP00000380612 ENST00000397472	Q8NB37 [Direct mapping] Parkinson disease 7 domain-containing protein 1 Show all	Enzymes Peptidases Cysteine-type peptidases Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0019172 [glyoxalase III activity] GO:0019243 [methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione] GO:0019249 [lactate biosynthetic process] GO:0070062 [extracellular exosome] Show all	250 aa 26.8 kDa	Yes	0
PDDC1-010 ENSP00000436417 ENST00000465313	H0YER3 [Direct mapping] Parkinson disease 7 domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		87 aa 8.9 kDa	No	0
PDDC1-012 ENSP00000437068 ENST00000528309	H0YF25 [Direct mapping] Parkinson disease 7 domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		162 aa 17.3 kDa	No	0
PDDC1-014 ENSP00000431183 ENST00000524550	Q8NB37 [Direct mapping] Parkinson disease 7 domain-containing protein 1 Show all	Enzymes Peptidases Cysteine-type peptidases Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0019172 [glyoxalase III activity] GO:0019243 [methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione] GO:0019249 [lactate biosynthetic process] GO:0070062 [extracellular exosome] Show all	184 aa 19.5 kDa	Yes	0
PDDC1-016 ENSP00000433322 ENST00000526325	E9PLI5 [Direct mapping] Parkinson disease 7 domain-containing protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		186 aa 19.7 kDa	Yes	0
PDDC1-017 ENSP00000434839 ENST00000526650	H0YE25 [Direct mapping] Parkinson disease 7 domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		144 aa 15.4 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.