Tissue expression of DEFB4B - Summary - The Human Protein Atlas

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DEFB4B

TISSUE

CELL

CANCER

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	DEFB4B
Gene description	Defensin, beta 4B
Protein class	Predicted secreted proteins Transporters
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (tonsil)
GTEx:	Group enriched (esophagus, salivary gland, lung)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (tonsil)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (esophagus, salivary gland, lung)

GENE INFORMATION
Gene name	DEFB4B (HGNC Symbol)
Synonyms	DEFB4P
Description	Defensin, beta 4B (HGNC Symbol)
Entrez gene summary	Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Oct 2014]
Chromosome	8
Cytoband	p23.1
Chromosome location (bp)	7414860 - 7416863
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177257 (version 83.38)
Entrez gene	100289462
UniProt	O15263 (UniProt - Evidence at protein level)
neXtProt	NX_O15263
Antibodypedia	DEFB4B antibodies

PROTEIN BROWSER

DEFB4B-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DEFB4B-001 ENSP00000424598 ENST00000318157	O15263 [Direct mapping] Beta-defensin 4A Show all	Transporters Transporter channels and pores MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] GO:0005796 [Golgi lumen] GO:0006935 [chemotaxis] GO:0006952 [defense response] GO:0006955 [immune response] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0042742 [defense response to bacterium] GO:0045087 [innate immune response] Show all	64 aa 7 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.