Expression of TIMM22 in cancer - Summary

CANCER ATLAS

Gene description

Translocase of inner mitochondrial membrane 22 homolog (yeast)

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Thyroid cancer

STAINING SUMMARY

HPA045138

GENE INFORMATION
Gene name	TIMM22 (HGNC Symbol)
Synonyms	TEX4
Description	Translocase of inner mitochondrial membrane 22 homolog (yeast) (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.3
Chromosome location (bp)	997117 - 1003671
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177370 (version 83.38)
Entrez gene	29928
UniProt	Q9Y584 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y584
Antibodypedia	TIMM22 antibodies

PROTEIN BROWSER

TIMM22-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TIMM22-001 ENSP00000320236 ENST00000327158	Q9Y584 [Direct mapping] Mitochondrial import inner membrane translocase subunit Tim22 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0006626 [protein targeting to mitochondrion] GO:0015266 [protein channel activity] GO:0016021 [integral component of membrane] GO:0030943 [mitochondrion targeting sequence binding] GO:0042721 [mitochondrial inner membrane protein insertion complex] GO:0044267 [cellular protein metabolic process] GO:0045039 [protein import into mitochondrial inner membrane] Show all	194 aa 20 kDa	No	2