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Acyl-CoA dehydrogenase family, member 9 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]
Q9H845 [Direct mapping] Acyl-CoA dehydrogenase family member 9, mitochondrial
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SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000062 [fatty-acyl-CoA binding] GO:0003995 [acyl-CoA dehydrogenase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0008152 [metabolic process] GO:0009055 [electron carrier activity] GO:0016627 [oxidoreductase activity, acting on the CH-CH group of donors] GO:0030425 [dendrite] GO:0032981 [mitochondrial respiratory chain complex I assembly] GO:0033539 [fatty acid beta-oxidation using acyl-CoA dehydrogenase] GO:0050660 [flavin adenine dinucleotide binding] GO:0052890 [oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor] GO:0055088 [lipid homeostasis] GO:0055114 [oxidation-reduction process]
