Cell atlas - THAP5 - The Human Protein Atlas

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THAP5

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	THAP5
Gene description	THAP domain containing 5
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (validated)

DATA RELIABILITY
Reliability score	Validated based on 1 antibody. HPA051488
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus.

Main location

Nucleus (validated)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA051488	A-431	Nucleoplasm
	HPA051488	U-2 OS	Nucleus
	HPA051488	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	THAP5 (HGNC Symbol)
Synonyms	DKFZp313O1132
Description	THAP domain containing 5 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q31.1
Chromosome location (bp)	108554543 - 108569750
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177683 (version 83.38)
Entrez gene	168451
UniProt	Q7Z6K1 (UniProt - Evidence at protein level)
neXtProt	NX_Q7Z6K1
Antibodypedia	THAP5 antibodies

PROTEIN BROWSER

THAP5-001	THAP5-002	THAP5-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
THAP5-001 ENSP00000400500 ENST00000415914	Q7Z6K1 [Direct mapping] THAP domain-containing protein 5 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002020 [protease binding] GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0007049 [cell cycle] GO:0045786 [negative regulation of cell cycle] GO:0046872 [metal ion binding] Show all	395 aa 45.4 kDa	No	0
THAP5-002 ENSP00000322440 ENST00000313516	Q7Z6K1 [Direct mapping] THAP domain-containing protein 5 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002020 [protease binding] GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0007049 [cell cycle] GO:0045786 [negative regulation of cell cycle] GO:0046872 [metal ion binding] Show all	353 aa 40.2 kDa	No	0
THAP5-003 ENSP00000415841 ENST00000438865	C9JIH7 [Direct mapping] THAP domain-containing protein 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	55 aa 6.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.