We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa (HGNC Symbol)
Entrez gene summary
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008]
P62875 [Direct mapping] DNA-directed RNA polymerases I, II, and III subunit RPABC5
Show all
Predicted intracellular proteins Plasma proteins RNA polymerase related proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000398 [mRNA splicing, via spliceosome] GO:0001054 [RNA polymerase I activity] GO:0001055 [RNA polymerase II activity] GO:0001056 [RNA polymerase III activity] GO:0003677 [DNA binding] GO:0003899 [DNA-directed RNA polymerase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005665 [DNA-directed RNA polymerase II, core complex] GO:0005666 [DNA-directed RNA polymerase III complex] GO:0005736 [DNA-directed RNA polymerase I complex] GO:0005829 [cytosol] GO:0006281 [DNA repair] GO:0006283 [transcription-coupled nucleotide-excision repair] GO:0006289 [nucleotide-excision repair] GO:0006351 [transcription, DNA-templated] GO:0006356 [regulation of transcription from RNA polymerase I promoter] GO:0006360 [transcription from RNA polymerase I promoter] GO:0006361 [transcription initiation from RNA polymerase I promoter] GO:0006362 [transcription elongation from RNA polymerase I promoter] GO:0006363 [termination of RNA polymerase I transcription] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0006368 [transcription elongation from RNA polymerase II promoter] GO:0006370 [7-methylguanosine mRNA capping] GO:0006383 [transcription from RNA polymerase III promoter] GO:0006385 [transcription elongation from RNA polymerase III promoter] GO:0006386 [termination of RNA polymerase III transcription] GO:0008270 [zinc ion binding] GO:0008380 [RNA splicing] GO:0010467 [gene expression] GO:0016032 [viral process] GO:0031047 [gene silencing by RNA] GO:0032481 [positive regulation of type I interferon production] GO:0034587 [piRNA metabolic process] GO:0035019 [somatic stem cell population maintenance] GO:0040029 [regulation of gene expression, epigenetic] GO:0045087 [innate immune response] GO:0045814 [negative regulation of gene expression, epigenetic] GO:0050434 [positive regulation of viral transcription]