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Most malignant cells displayed weak cytoplasmic staining or were negative. Several malignant melanomas, prostate and pancreatic cancers were moderately stained.
GENE INFORMATION
Gene name
DEFB125 (HGNC Symbol)
Synonyms
DEFB-25
Description
Defensin, beta 125 (HGNC Symbol)
Entrez gene summary
Defensins are cysteine-rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. [provided by RefSeq, Nov 2014]