Tissue expression of OTOS - Summary - The Human Protein Atlas

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OTOS

TISSUE

CELL

CANCER

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	OTOS
Gene description	Otospiralin
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (thyroid gland)
GTEx:	Group enriched (pituitary gland, thyroid gland)
FANTOM5:	Group enriched (pituitary gland, thyroid gland)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (thyroid gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (pituitary gland, thyroid gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (pituitary gland, thyroid gland)

GENE INFORMATION
Gene name	OTOS (HGNC Symbol)
Synonyms	OTOSP
Description	Otospiralin (HGNC Symbol)
Entrez gene summary	Otospiralin is synthesized by nonsensory cells (fibrocytes) of the inner ear, and downregulation of otospiralin in guinea pigs leads to deafness (Lavigne-Rebillard et al., 2003 [PubMed 12687421]).[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband	q37.3
Chromosome location (bp)	240139026 - 240144562
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000178602 (version 83.38)
Entrez gene	150677
UniProt	Q8NHW6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NHW6
Antibodypedia	OTOS antibodies

PROTEIN BROWSER

OTOS-001	OTOS-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OTOS-001 ENSP00000375849 ENST00000391989	Q8NHW6 [Direct mapping] Otospiralin Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] GO:0007605 [sensory perception of sound] Show all	89 aa 9.9 kDa	Yes	0
OTOS-201 ENSP00000322486 ENST00000319460	Q8NHW6 [Direct mapping] Otospiralin Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] GO:0007605 [sensory perception of sound] Show all	89 aa 9.9 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.