Expression of GRINA in cancer - Summary

CANCER ATLAS

Gene description

Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA036980	HPA036981

GENE INFORMATION
Gene name	GRINA (HGNC Symbol)
Synonyms	HNRGW, LFG1, NMDARA1, TMBIM3
Description	Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q24.3
Chromosome location (bp)	143990058 - 143993415
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000178719 (version 83.38)
Entrez gene	2907
UniProt	Q7Z429 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7Z429
Antibodypedia	GRINA antibodies

PROTEIN BROWSER

GRINA-001	GRINA-004	GRINA-005	GRINA-007	GRINA-009	GRINA-010	GRINA-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GRINA-001 ENSP00000378507 ENST00000395068	Q7Z429 [Direct mapping] Protein lifeguard 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	371 aa 41.2 kDa	No	7
GRINA-004 ENSP00000432706 ENST00000529301	E9PPG3 [Direct mapping] Protein lifeguard 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	274 aa 30.2 kDa	No	4
GRINA-005 ENSP00000436807 ENST00000530898	E9PQF8 [Direct mapping] Protein lifeguard 1 Show all	Predicted intracellular proteins Show all		101 aa 10.8 kDa	No	0
GRINA-007 ENSP00000435901 ENST00000534791	H0YEI4 [Direct mapping] Protein lifeguard 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	351 aa 39 kDa	No	3
GRINA-009 ENSP00000432095 ENST00000533044	H0YCP9 [Direct mapping] Protein lifeguard 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	188 aa 21 kDa	No	5
GRINA-010 ENSP00000431217 ENST00000527194	H0YC98 [Direct mapping] Protein lifeguard 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	184 aa 20.4 kDa	No	6
GRINA-201 ENSP00000314380 ENST00000313269	Q7Z429 [Direct mapping] Protein lifeguard 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0016021 [integral component of membrane] GO:0032469 [endoplasmic reticulum calcium ion homeostasis] GO:0044325 [ion channel binding] GO:1902236 [negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway] Show all	371 aa 41.2 kDa	No	7