Tissue expression of TMEM52 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	TMEM52
Gene description	Transmembrane protein 52
Protein class	Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins
Predicted localization	Intracellular,Membrane,Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (skeletal muscle, pancreas)
GTEx:	Group enriched (pancreas, skeletal muscle, adrenal gland, testis)
FANTOM5:	Tissue enhanced (pancreas, skeletal muscle)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (skeletal muscle, pancreas)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (pancreas, skeletal muscle, adrenal gland, testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (pancreas, skeletal muscle)

GENE INFORMATION
Gene name	TMEM52
Synonyms
Description	Transmembrane protein 52 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p36.33
Chromosome location (bp)	1917590 - 1919273
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000178821 (version 83.38)
Entrez gene	339456
UniProt	Q8NDY8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NDY8
Antibodypedia	TMEM52 antibodies

PROTEIN BROWSER

TMEM52-001	TMEM52-002	TMEM52-004	TMEM52-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM52-001 ENSP00000311122 ENST00000310991	Q8NDY8 [Direct mapping] Transmembrane protein 52 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	209 aa 22.1 kDa	Yes	1
TMEM52-002 ENSP00000409669 ENST00000416272	B1AKR3 [Direct mapping] Transmembrane protein 52 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	103 aa 10.6 kDa	Yes	1
TMEM52-004 ENSP00000367865 ENST00000378602	Q8NDY8 [Direct mapping] Transmembrane protein 52 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0016021 [integral component of membrane] Show all	194 aa 20.9 kDa	Yes	0
TMEM52-005 ENSP00000367861 ENST00000378598	B1AKR2 [Direct mapping] Transmembrane protein 52 Show all	Predicted intracellular proteins Show all		124 aa 13.7 kDa	No	0