Expression of TPRX1 in cancer - Summary

CANCER ATLAS

Gene description

Tetra-peptide repeat homeobox 1

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA044922

GENE INFORMATION
Gene name	TPRX1 (HGNC Symbol)
Synonyms	FLJ40321
Description	Tetra-peptide repeat homeobox 1 (HGNC Symbol)
Entrez gene summary	Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the TPRX homeobox gene family. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	q13.33
Chromosome location (bp)	47801243 - 47819051
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000178928 (version 83.38)
Entrez gene	284355
UniProt	Q8N7U7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N7U7
Antibodypedia	TPRX1 antibodies

PROTEIN BROWSER

TPRX1-001	TPRX1-201	TPRX1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TPRX1-001 ENSP00000323455 ENST00000322175	Q8N7U7 [Direct mapping] Tetra-peptide repeat homeobox protein 1 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	411 aa 40.6 kDa	No	0
TPRX1-201 ENSP00000438832 ENST00000535759	D2CFI5 [Direct mapping] CRX like homeobox 2; Tetra-peptide repeat homeobox protein 1 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0043565 [sequence-specific DNA binding] Show all	508 aa 51.9 kDa	No	0
TPRX1-202 ENSP00000438712 ENST00000543508	B7ZMM8 [Direct mapping] TPRX1 protein; Tetra-peptide repeat homeobox protein 1 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] Show all	401 aa 39.7 kDa	No	0