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Cancer tissues displayed weak to moderate cytoplasmic positivity. Additional membranous positivity was observed in few cases of colorectal, thyroid, urothelial and prostate cancers. Thyroid and several cases of skin cancers along with a few cases of gliomas, melanomas, colorectal and renal cancers were strongly stained. Most lymphomas were negative.
GENE INFORMATION
Gene name
FJX1 (HGNC Symbol)
Synonyms
FLJ22416, FLJ25593
Description
Four jointed box 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is the human ortholog of mouse and Drosophila four-jointed gene product. The Drosophila protein is important for growth and differentiation of legs and wings, and for proper development of the eyes. The exact function of this gene in humans is not known. [provided by RefSeq, Jul 2008]
