Cell atlas - PCED1B - The Human Protein Atlas

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PCED1B

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus
	Vesicles

Human cell
	Golgi Apparatus
	Vesicles

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GENERAL INFORMATION
Gene name	PCED1B
Gene description	PC-esterase domain containing 1B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the Golgi apparatus. In addition localized to vesicles.
RNA cell category	Cell line enhanced (A549, K-562)
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (approved)
Additional location	In addition localized to the Vesicles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA043901
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (A549, K-562) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the Golgi apparatus. In addition localized to vesicles.

Main location

Golgi apparatus (approved)

Additional location

Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA043901	A549	Golgi apparatus
	HPA043901	A549	Vesicles
	HPA043901	HaCaT	Golgi apparatus
	HPA043901	HaCaT	Vesicles
	HPA043901	U-2 OS	Vesicles

GENE INFORMATION
Gene name	PCED1B (HGNC Symbol)
Synonyms	FAM113B, MGC16044
Description	PC-esterase domain containing 1B (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that belongs to the GDSL/SGNH-like acyl-esterase family. Members of this family are hydrolases thought to function in modification of biopolymers on the cell surface. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Chromosome	12
Cytoband	q13.11
Chromosome location (bp)	47079603 - 47236662
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000179715 (version 83.38)
Entrez gene	91523
UniProt	Q96HM7 (UniProt - Evidence at protein level)
neXtProt	NX_Q96HM7
Antibodypedia	PCED1B antibodies

PROTEIN BROWSER

PCED1B-001	PCED1B-003	PCED1B-004	PCED1B-005	PCED1B-006	PCED1B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PCED1B-001 ENSP00000446688 ENST00000546455	Q96HM7 [Direct mapping] PC-esterase domain-containing protein 1B A0A024R115 [Target identity:100%; Query identity:100%] Family with sequence similarity 113, member B, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	432 aa 49.7 kDa	No	0
PCED1B-003 ENSP00000448693 ENST00000548348	F8VRF7 [Direct mapping] PC-esterase domain-containing protein 1B Show all	Predicted intracellular proteins Show all		189 aa 21.7 kDa	No	0
PCED1B-004 ENSP00000449680 ENST00000549500	A0A0E3D6L9 [Direct mapping] PC-esterase domain-containing protein 1B Show all	Predicted intracellular proteins Show all		167 aa 19.6 kDa	No	0
PCED1B-005 ENSP00000448000 ENST00000549630	F8VUD2 [Direct mapping] PC-esterase domain-containing protein 1B Show all	Predicted intracellular proteins Show all		168 aa 19.7 kDa	No	0
PCED1B-006 ENSP00000448926 ENST00000551777	F8VYL8 [Direct mapping] PC-esterase domain-containing protein 1B Show all	Predicted intracellular proteins Show all		58 aa 6.7 kDa	No	0
PCED1B-201 ENSP00000396040 ENST00000432328	Q96HM7 [Direct mapping] PC-esterase domain-containing protein 1B A0A024R115 [Target identity:100%; Query identity:100%] Family with sequence similarity 113, member B, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	432 aa 49.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.