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FOXS1

GENERAL INFORMATION

Gene name

 FOXS1

Gene description

 Forkhead box S1

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA042475
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 FOXS1 (HGNC Symbol)

Synonyms

 FKHL18, FREAC10

Description

 Forkhead box S1 (HGNC Symbol)

Entrez gene summary

 The forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a forkhead domain and is found predominantly in aorta and kidney. The function of the encoded protein is unknown. [provided by RefSeq, Jul 2008]

Chromosome

 20

Cytoband

 q11.21

Chromosome location (bp)

 31844301 - 31845619

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000179772 (version 83.38)

Entrez gene

 2307

UniProt

 O43638 (UniProt - Evidence at transcript level)

neXtProt

 NX_O43638

Antibodypedia

 FOXS1 antibodies

PROTEIN BROWSER
FOXS1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FOXS1-001
ENSP00000365145
ENST00000375978
O43638 [Direct mapping]
Forkhead box protein S1
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Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
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GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0001568 [blood vessel development]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0030154 [cell differentiation]
GO:0040018 [positive regulation of multicellular organism growth]
GO:0043433 [negative regulation of sequence-specific DNA binding transcription factor activity]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0050885 [neuromuscular process controlling balance]
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 330 aa
35.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.