Expression of ATOH7 in cancer - Summary

CANCER ATLAS

Gene description

Atonal bHLH transcription factor 7

Protein class

Disease related genes, Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA027008

GENE INFORMATION
Gene name	ATOH7 (HGNC Symbol)
Synonyms	bHLHa13, Math5
Description	Atonal bHLH transcription factor 7 (HGNC Symbol)
Entrez gene summary	This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011]
Chromosome	10
Cytoband	q21.3
Chromosome location (bp)	68230624 - 68232103
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000179774 (version 83.38)
Entrez gene	220202
UniProt	Q8N100 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N100
Antibodypedia	ATOH7 antibodies

PROTEIN BROWSER

ATOH7-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATOH7-001 ENSP00000362777 ENST00000373673	Q8N100 [Direct mapping] Protein atonal homolog 7 F1T0H4 [Target identity:100%; Query identity:100%] HCG1795924; Protein atonal homolog 7 Show all	Predicted intracellular proteins Transcription factors Basic domains Disease related genes Show all	GO:0003407 [neural retina development] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007623 [circadian rhythm] GO:0009649 [entrainment of circadian clock] GO:0021554 [optic nerve development] GO:0030154 [cell differentiation] GO:0046983 [protein dimerization activity] Show all	152 aa 16.9 kDa	No	0