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RCC1

CANCER ATLAS

Gene description

 Regulator of chromosome condensation 1

Protein class

 Plasma proteins, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA027573
HPA027574
CAB015413

GENE INFORMATION

Gene name

 RCC1 (HGNC Symbol)

Synonyms

 CHC1

Description

 Regulator of chromosome condensation 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p35.3

Chromosome location (bp)

 28505943 - 28539300

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000180198 (version 83.38)

Entrez gene

 1104

UniProt

 P18754 (UniProt - Evidence at protein level)

neXtProt

 NX_P18754

Antibodypedia

 RCC1 antibodies

PROTEIN BROWSER
RCC1-001
RCC1-003
RCC1-004
RCC1-005
RCC1-006
RCC1-007
RCC1-008
RCC1-011
RCC1-012
RCC1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RCC1-001
ENSP00000362938
ENST00000373832
P18754 [Direct mapping]
Regulator of chromosome condensation
Q5T081 [Target identity:100%; Query identity:100%]
CHC1 protein; Regulator of chromosome condensation 1, isoform CRA_b
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000790 [nuclear chromatin]
GO:0000794 [condensed nuclear chromosome]
GO:0003682 [chromatin binding]
GO:0005087 [Ran guanyl-nucleotide exchange factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007052 [mitotic spindle organization]
GO:0007059 [chromosome segregation]
GO:0007067 [mitotic nuclear division]
GO:0007088 [regulation of mitotic nuclear division]
GO:0016032 [viral process]
GO:0031492 [nucleosomal DNA binding]
GO:0031965 [nuclear membrane]
GO:0042393 [histone binding]
GO:0043547 [positive regulation of GTPase activity]
GO:0051225 [spindle assembly]
GO:0051301 [cell division]
Show all
 421 aa
45 kDa 		No 0
RCC1-003
ENSP00000362939
ENST00000373833
P18754 [Direct mapping]
Regulator of chromosome condensation
Q5T081 [Target identity:100%; Query identity:100%]
CHC1 protein; Regulator of chromosome condensation 1, isoform CRA_b
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000790 [nuclear chromatin]
GO:0000794 [condensed nuclear chromosome]
GO:0003682 [chromatin binding]
GO:0005087 [Ran guanyl-nucleotide exchange factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007052 [mitotic spindle organization]
GO:0007059 [chromosome segregation]
GO:0007067 [mitotic nuclear division]
GO:0007088 [regulation of mitotic nuclear division]
GO:0016032 [viral process]
GO:0031492 [nucleosomal DNA binding]
GO:0031965 [nuclear membrane]
GO:0042393 [histone binding]
GO:0043547 [positive regulation of GTPase activity]
GO:0051225 [spindle assembly]
GO:0051301 [cell division]
Show all
 421 aa
45 kDa 		No 0
RCC1-004
ENSP00000362937
ENST00000373831
P18754 [Direct mapping]
Regulator of chromosome condensation
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000790 [nuclear chromatin]
GO:0000794 [condensed nuclear chromosome]
GO:0003682 [chromatin binding]
GO:0005087 [Ran guanyl-nucleotide exchange factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007052 [mitotic spindle organization]
GO:0007059 [chromosome segregation]
GO:0007067 [mitotic nuclear division]
GO:0007088 [regulation of mitotic nuclear division]
GO:0016032 [viral process]
GO:0031492 [nucleosomal DNA binding]
GO:0031965 [nuclear membrane]
GO:0042393 [histone binding]
GO:0043547 [positive regulation of GTPase activity]
GO:0051225 [spindle assembly]
GO:0051301 [cell division]
Show all
 452 aa
48.1 kDa 		No 0
RCC1-005
ENSP00000402260
ENST00000419074
C9JMJ4 [Direct mapping]
Regulator of chromosome condensation
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0031965 [nuclear membrane]
Show all
 272 aa
29.2 kDa 		No 0
RCC1-006
ENSP00000413644
ENST00000411533
C9JW69 [Direct mapping]
Regulator of chromosome condensation
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0031965 [nuclear membrane]
Show all
 372 aa
39.6 kDa 		No 0
RCC1-007
ENSP00000405258
ENST00000434290
C9J3R0 [Direct mapping]
Regulator of chromosome condensation
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
Show all
 273 aa
29.6 kDa 		No 0
RCC1-008
ENSP00000394650
ENST00000430407
C9JQZ4 [Direct mapping]
Regulator of chromosome condensation
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0031965 [nuclear membrane]
Show all
 283 aa
30.3 kDa 		No 0
RCC1-011
ENSP00000472057
ENST00000486790
M0R1Q8 [Direct mapping]
Regulator of chromosome condensation
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 148 aa
15.9 kDa 		No 0
RCC1-012
ENSP00000402740
ENST00000427469
C9JRH2 [Direct mapping]
Regulator of chromosome condensation
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0031965 [nuclear membrane]
Show all
 230 aa
24.5 kDa 		No 0
RCC1-201
ENSP00000381931
ENST00000398958
P18754 [Direct mapping]
Regulator of chromosome condensation
Q5T081 [Target identity:100%; Query identity:100%]
CHC1 protein; Regulator of chromosome condensation 1, isoform CRA_b
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000790 [nuclear chromatin]
GO:0000794 [condensed nuclear chromosome]
GO:0003682 [chromatin binding]
GO:0005087 [Ran guanyl-nucleotide exchange factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007052 [mitotic spindle organization]
GO:0007059 [chromosome segregation]
GO:0007067 [mitotic nuclear division]
GO:0007088 [regulation of mitotic nuclear division]
GO:0016032 [viral process]
GO:0031492 [nucleosomal DNA binding]
GO:0031965 [nuclear membrane]
GO:0042393 [histone binding]
GO:0043547 [positive regulation of GTPase activity]
GO:0051225 [spindle assembly]
GO:0051301 [cell division]
Show all
 421 aa
45 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.