Expression of ZSCAN4 in cancer - Summary

CANCER ATLAS

Gene description

Zinc finger and SCAN domain containing 4

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA006491

GENE INFORMATION
Gene name	ZSCAN4 (HGNC Symbol)
Synonyms	FLJ35105, ZNF494
Description	Zinc finger and SCAN domain containing 4 (HGNC Symbol)
Entrez gene summary	The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).[supplied by OMIM, May 2010]
Chromosome	19
Cytoband	q13.43
Chromosome location (bp)	57668935 - 57679152
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000180532 (version 83.38)
Entrez gene	201516
UniProt	Q8NAM6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NAM6
Antibodypedia	ZSCAN4 antibodies

PROTEIN BROWSER

ZSCAN4-001	ZSCAN4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZSCAN4-001 ENSP00000321963 ENST00000318203	Q8NAM6 [Direct mapping] Zinc finger and SCAN domain-containing protein 4 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000784 [nuclear chromosome, telomeric region] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0010833 [telomere maintenance via telomere lengthening] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] Show all	433 aa 49 kDa	No	0
ZSCAN4-201 ENSP00000480210 ENST00000612521	Q8NAM6 [Direct mapping] Zinc finger and SCAN domain-containing protein 4 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000784 [nuclear chromosome, telomeric region] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0010833 [telomere maintenance via telomere lengthening] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] Show all	433 aa 49 kDa	No	0