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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

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Searches

Tissue

Cell type

Expression

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Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

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Antibodies

Column

 
 
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BHLHA15
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    TISSUE

  • CELL

  • CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

BHLHA15

Gene description

Basic helix-loop-helix family, member a15

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Group enriched (pancreas, salivary gland)
GTEx:Tissue enriched (pancreas)
FANTOM5:Group enriched (pancreas, salivary gland)

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression in glandular cells in stomach, salivary gland, exocrine pancreas and a subset of non-germinal center cells.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 2 antibodies.
HPA047834 , CAB034083
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (pancreas, salivary gland)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (pancreas)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (pancreas, salivary gland)

GENE INFORMATION

Gene name

BHLHA15 (HGNC Symbol)

Synonyms

bHLHa15, BHLHB8, MIST1

Description

Basic helix-loop-helix family, member a15 (HGNC Symbol)

Entrez gene summary

Chromosome

7

Cytoband

q21.3

Chromosome location (bp)

98211427 - 98212979

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000180535 (version 83.38)

Entrez gene

168620

UniProt

Q7RTS1 (UniProt - Evidence at protein level)

neXtProt

NX_Q7RTS1

Antibodypedia

BHLHA15 antibodies

PROTEIN BROWSER

BHLHA15-001
BHLHA15-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BHLHA15-001
ENSP00000326391
ENST00000314018
Q7RTS1 [Direct mapping]
Class A basic helix-loop-helix protein 15
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Show all
GO:0005634 [nucleus]
GO:0010832 [negative regulation of myotube differentiation]
GO:0030968 [endoplasmic reticulum unfolded protein response]
GO:0042149 [cellular response to glucose starvation]
GO:0046983 [protein dimerization activity]
Show all
189 aa
20.8 kDa
No 0
BHLHA15-003
ENSP00000476312
ENST00000609256
Q7RTS1 [Direct mapping]
Class A basic helix-loop-helix protein 15
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006851 [mitochondrial calcium ion transport]
GO:0007030 [Golgi organization]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007267 [cell-cell signaling]
GO:0010832 [negative regulation of myotube differentiation]
GO:0019722 [calcium-mediated signaling]
GO:0030968 [endoplasmic reticulum unfolded protein response]
GO:0042149 [cellular response to glucose starvation]
GO:0042593 [glucose homeostasis]
GO:0042803 [protein homodimerization activity]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046983 [protein dimerization activity]
GO:0048312 [intracellular distribution of mitochondria]
GO:0048469 [cell maturation]
Show all
189 aa
20.8 kDa
No 0

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