We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation. [provided by RefSeq, Jul 2008]
Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001501 [skeletal system development] GO:0003677 [DNA binding] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008284 [positive regulation of cell proliferation] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0019907 [cyclin-dependent protein kinase activating kinase holoenzyme complex] GO:0021520 [spinal cord motor neuron cell fate specification] GO:0030326 [embryonic limb morphogenesis] GO:0043565 [sequence-specific DNA binding] GO:0050905 [neuromuscular process]
