Cell atlas - ZNF443 - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ZNF443
Gene description	Zinc finger protein 443
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the microtubule organizing center. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (uncertain)
Additional location	In addition localized to the Microtubule organizing center (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA018683
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the microtubule organizing center. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nucleoplasm (uncertain)

Additional location

Microtubule organizing center (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA018683	Hep G2	Nucleoplasm
HPA018683	RT4	Nucleoplasm
HPA018683	RT4	Microtubule organizing center
HPA018683	U-2 OS	Nucleoplasm
HPA018683	U-2 OS	Microtubule organizing center

GENE INFORMATION
Gene name	ZNF443 (HGNC Symbol)
Synonyms	ZK1
Description	Zinc finger protein 443 (HGNC Symbol)
Entrez gene summary	Zinc finger proteins (ZNFs) bind DNA and, through this binding, regulate gene transcription. Most ZNFs contain conserved C2H2 motifs and are classified as Kruppel-type zinc fingers. For a general description of these proteins, see ZNF91 (MIM 603971).[supplied by OMIM, Jul 2002]
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	12429707 - 12441112
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000180855 (version 83.38)
Entrez gene	10224
UniProt	Q9Y2A4 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y2A4
Antibodypedia	ZNF443 antibodies

PROTEIN BROWSER

ZNF443-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF443-001 ENSP00000301547 ENST00000301547	Q9Y2A4 [Direct mapping] Zinc finger protein 443 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006915 [apoptotic process] GO:0006950 [response to stress] GO:0046872 [metal ion binding] Show all	671 aa 77.5 kDa	No	0