Expression of HIGD1A in cancer - Summary

CANCER ATLAS

Gene description

HIG1 hypoxia inducible domain family, member 1A

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA043336

GENE INFORMATION
Gene name	HIGD1A (HGNC Symbol)
Synonyms	DKFZP564K247, HIG1
Description	HIG1 hypoxia inducible domain family, member 1A (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	p22.1
Chromosome location (bp)	42784298 - 42804531
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000181061 (version 83.38)
Entrez gene	25994
UniProt	Q9Y241 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y241
Antibodypedia	HIGD1A antibodies

PROTEIN BROWSER

HIGD1A-001	HIGD1A-002	HIGD1A-005	HIGD1A-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HIGD1A-001 ENSP00000319393 ENST00000321331	Q9Y241 [Direct mapping] HIG1 domain family member 1A, mitochondrial A0A024R2M9 [Target identity:100%; Query identity:100%] HIG1 domain family, member 1A, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005743 [mitochondrial inner membrane] GO:0016021 [integral component of membrane] GO:0043066 [negative regulation of apoptotic process] GO:0043234 [protein complex] GO:0055114 [oxidation-reduction process] GO:0070469 [respiratory chain] Show all	93 aa 10.1 kDa	No	2
HIGD1A-002 ENSP00000402160 ENST00000418900	Q9Y241 [Direct mapping] HIG1 domain family member 1A, mitochondrial A0A024R2M9 [Target identity:100%; Query identity:100%] HIG1 domain family, member 1A, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005743 [mitochondrial inner membrane] GO:0016021 [integral component of membrane] GO:0043066 [negative regulation of apoptotic process] GO:0043234 [protein complex] GO:0055114 [oxidation-reduction process] GO:0070469 [respiratory chain] Show all	93 aa 10.1 kDa	No	2
HIGD1A-005 ENSP00000408289 ENST00000430190	C9JNU6 [Direct mapping] HIG1 domain family member 1A, mitochondrial Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	96 aa 10.4 kDa	No	2
HIGD1A-006 ENSP00000398064 ENST00000452906	Q9Y241 [Direct mapping] HIG1 domain family member 1A, mitochondrial Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005743 [mitochondrial inner membrane] GO:0016021 [integral component of membrane] GO:0043066 [negative regulation of apoptotic process] GO:0043234 [protein complex] GO:0055114 [oxidation-reduction process] GO:0070469 [respiratory chain] Show all	107 aa 11.8 kDa	No	2