Expression of OFCC1 in cancer - Summary

CANCER ATLAS

Gene description

Orofacial cleft 1 candidate 1

Protein class

Disease related genes, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA035725

GENE INFORMATION
Gene name	OFCC1 (HGNC Symbol)
Synonyms	MRDS1
Description	Orofacial cleft 1 candidate 1 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p24.3
Chromosome location (bp)	9596110 - 10211608
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000181355 (version 83.38)
Entrez gene
UniProt	Q8IZS5 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IZS5
Antibodypedia	OFCC1 antibodies

PROTEIN BROWSER

OFCC1-001	OFCC1-004	OFCC1-006	OFCC1-010	OFCC1-017	OFCC1-201	OFCC1-202	OFCC1-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OFCC1-001 ENSP00000419718 ENST00000460363	Q8IZS0 [Direct mapping] MRDS1 protein; Orofacial cleft 1 candidate gene 1 protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0015630 [microtubule cytoskeleton] GO:0016021 [integral component of membrane] GO:0048471 [perinuclear region of cytoplasm] Show all	300 aa 34.2 kDa	No	1
OFCC1-004 ENSP00000417933 ENST00000485268		Predicted intracellular proteins Show all		4 aa 0.6 kDa	No	0
OFCC1-006 ENSP00000418251 ENST00000491508	Q8IZS5 [Direct mapping] Orofacial cleft 1 candidate gene 1 protein Show all	Predicted intracellular proteins Disease related genes Show all	GO:0005515 [protein binding] Show all	208 aa 23.4 kDa	No	0
OFCC1-010 ENSP00000418013 ENST00000492169	H0Y878 [Direct mapping] Orofacial cleft 1 candidate gene 1 protein Show all	Predicted intracellular proteins Show all		187 aa 21 kDa	No	0
OFCC1-017 ENSP00000418286 ENST00000481704	Q8IZS4 [Direct mapping] MRDS1 protein; Orofacial cleft 1 candidate gene 1 protein Show all	Predicted intracellular proteins Show all		22 aa 2.6 kDa	No	0
OFCC1-201 ENSP00000325053 ENST00000316020	A0A0A0MR58 [Direct mapping] Orofacial cleft 1 candidate gene 1 protein Show all	Predicted intracellular proteins Show all		231 aa 26.8 kDa	No	0
OFCC1-202 ENSP00000484598 ENST00000611763	A0A087X205 [Direct mapping] Orofacial cleft 1 candidate gene 1 protein Show all	Predicted intracellular proteins Show all		235 aa 27.2 kDa	No	0
OFCC1-203 ENSP00000480108 ENST00000622909	A0A087WWC2 [Direct mapping] Orofacial cleft 1 candidate gene 1 protein Show all	Predicted intracellular proteins Show all		235 aa 27.2 kDa	No	0