Expression of GPR135 in cancer - Summary

CANCER ATLAS

Gene description

G protein-coupled receptor 135

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA045337

GENE INFORMATION
Gene name	GPR135 (HGNC Symbol)
Synonyms	HUMNPIIY20, PAFR
Description	G protein-coupled receptor 135 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q23.1
Chromosome location (bp)	59429022 - 59465342
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000181619 (version 83.38)
Entrez gene	64582
UniProt	Q8IZ08 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IZ08
Antibodypedia	GPR135 antibodies

PROTEIN BROWSER

GPR135-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR135-002 ENSP00000378548 ENST00000395116	Q8IZ08 [Direct mapping] Probable G-protein coupled receptor 135 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	494 aa 51.7 kDa	No	7