Expression of P2RY13 in cancer - Summary

CANCER ATLAS

Gene description

Purinergic receptor P2Y, G-protein coupled, 13

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA049047

GENE INFORMATION
Gene name	P2RY13 (HGNC Symbol)
Synonyms	FKSG77, GPR86, GPR94, P2Y13
Description	Purinergic receptor P2Y, G-protein coupled, 13 (HGNC Symbol)
Entrez gene summary	The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Sep 2008]
Chromosome	3
Cytoband	q25.1
Chromosome location (bp)	151326312 - 151329548
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000181631 (version 83.38)
Entrez gene	53829
UniProt	Q9BPV8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BPV8
Antibodypedia	P2RY13 antibodies

PROTEIN BROWSER

P2RY13-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
P2RY13-001 ENSP00000320376 ENST00000325602	Q9BPV8 [Direct mapping] P2Y purinoceptor 13 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Adenosine and adenine nucleotide receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005783 [endoplasmic reticulum] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0035589 [G-protein coupled purinergic nucleotide receptor signaling pathway] GO:0045028 [G-protein coupled purinergic nucleotide receptor activity] GO:0071407 [cellular response to organic cyclic compound] Show all	354 aa 40.8 kDa	No	7