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Several gliomas along with a few breast, prostate, urothelial and testis cancers weak to moderate cytoplasmic positivity. Weak to moderate cytoplasmic and membranous staining was observed in a few colorectal cancers. Remaining cancer tissues were negative
GENE INFORMATION
Gene name
OR4P4 (HGNC Symbol)
Synonyms
OR4P3P
Description
Olfactory receptor, family 4, subfamily P, member 4 (HGNC Symbol)
Entrez gene summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
