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Most cancers showed moderate cytoplasmic and nuclear positivity. Cases of liver cancers along with rare breast, endometrial, carcinoid and urothelial cancers showed strong positivity.
GENE INFORMATION
Gene name
OR4C15
Synonyms
Description
Olfactory receptor, family 4, subfamily C, member 15 (HGNC Symbol)
Entrez gene summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
