Cell atlas - TDRKH - The Human Protein Atlas

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TDRKH

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Centrosome
	Cytosol

Human cell
	Centrosome
	Cytosol

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GENERAL INFORMATION
Gene name	TDRKH
Gene description	Tudor and KH domain containing
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol. In addition localized to the centrosome.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)
Additional location	In addition localized to the Centrosome (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA019625
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol. In addition localized to the centrosome.

Main location

Cytosol (approved)

Additional location

Centrosome (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA019625	A-431	Cytosol
	HPA019625	U-2 OS	Cytosol
	HPA019625	U-251 MG	Centrosome
	HPA019625	U-251 MG	Cytosol

GENE INFORMATION
Gene name	TDRKH (HGNC Symbol)
Synonyms	TDRD2
Description	Tudor and KH domain containing (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q21.3
Chromosome location (bp)	151770107 - 151791416
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000182134 (version 83.38)
Entrez gene	11022
UniProt	Q9Y2W6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2W6
Antibodypedia	TDRKH antibodies

PROTEIN BROWSER

TDRKH-001	TDRKH-002	TDRKH-003	TDRKH-004	TDRKH-005	TDRKH-009	TDRKH-013	TDRKH-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TDRKH-001 ENSP00000357815 ENST00000368824	Q9Y2W6 [Direct mapping] Tudor and KH domain-containing protein Show all	Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005739 [mitochondrion] GO:0007140 [male meiosis] GO:0007283 [spermatogenesis] GO:0009566 [fertilization] GO:0010467 [gene expression] GO:0030154 [cell differentiation] GO:0031047 [gene silencing by RNA] GO:0034587 [piRNA metabolic process] GO:0043046 [DNA methylation involved in gamete generation] GO:0071546 [pi-body] GO:0071547 [piP-body] Show all	561 aa 62 kDa	No	0
TDRKH-002 ENSP00000357819 ENST00000368827	Q9Y2W6 [Direct mapping] Tudor and KH domain-containing protein Show all	Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005739 [mitochondrion] GO:0007140 [male meiosis] GO:0007283 [spermatogenesis] GO:0009566 [fertilization] GO:0010467 [gene expression] GO:0030154 [cell differentiation] GO:0031047 [gene silencing by RNA] GO:0034587 [piRNA metabolic process] GO:0043046 [DNA methylation involved in gamete generation] GO:0071546 [pi-body] GO:0071547 [piP-body] Show all	561 aa 62 kDa	No	0
TDRKH-003 ENSP00000357813 ENST00000368823	Q5SZR4 [Direct mapping] Tudor and KH domain containing, isoform CRA_a; Tudor and KH domain-containing protein Show all	Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0016021 [integral component of membrane] Show all	557 aa 61.5 kDa	No	0
TDRKH-004 ENSP00000357817 ENST00000368825	Q9Y2W6 [Direct mapping] Tudor and KH domain-containing protein Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005739 [mitochondrion] GO:0007140 [male meiosis] GO:0007283 [spermatogenesis] GO:0009566 [fertilization] GO:0010467 [gene expression] GO:0030154 [cell differentiation] GO:0031047 [gene silencing by RNA] GO:0034587 [piRNA metabolic process] GO:0043046 [DNA methylation involved in gamete generation] GO:0071546 [pi-body] GO:0071547 [piP-body] Show all	516 aa 57.2 kDa	No	0
TDRKH-005 ENSP00000357812 ENST00000368822	Q9Y2W6 [Direct mapping] Tudor and KH domain-containing protein Show all	Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0007140 [male meiosis] GO:0007283 [spermatogenesis] GO:0009566 [fertilization] GO:0010467 [gene expression] GO:0030154 [cell differentiation] GO:0031047 [gene silencing by RNA] GO:0034587 [piRNA metabolic process] GO:0043046 [DNA methylation involved in gamete generation] GO:0071546 [pi-body] GO:0071547 [piP-body] Show all	561 aa 62 kDa	No	0
TDRKH-009 ENSP00000395718 ENST00000458431	Q9Y2W6 [Direct mapping] Tudor and KH domain-containing protein Show all	Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005739 [mitochondrion] GO:0007140 [male meiosis] GO:0007283 [spermatogenesis] GO:0009566 [fertilization] GO:0010467 [gene expression] GO:0030154 [cell differentiation] GO:0031047 [gene silencing by RNA] GO:0034587 [piRNA metabolic process] GO:0043046 [DNA methylation involved in gamete generation] GO:0071546 [pi-body] GO:0071547 [piP-body] Show all	561 aa 62 kDa	No	0
TDRKH-013 ENSP00000431557 ENST00000526378	E9PKN8 [Direct mapping] Tudor and KH domain-containing protein Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0016021 [integral component of membrane] Show all	131 aa 14.6 kDa	No	0
TDRKH-201 ENSP00000416645 ENST00000440583	F6TB26 [Direct mapping] Tudor and KH domain-containing protein Show all	Phobius predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0016021 [integral component of membrane] Show all	605 aa 67 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.