Expression of RXFP3 in cancer - Summary

CANCER ATLAS

Gene description

Relaxin/insulin-like family peptide receptor 3

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA027833

GENE INFORMATION
Gene name	RXFP3 (HGNC Symbol)
Synonyms	GPCR135, RLN3R1, RXFPR3, SALPR
Description	Relaxin/insulin-like family peptide receptor 3 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	p13.2
Chromosome location (bp)	33936386 - 33938237
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000182631 (version 83.38)
Entrez gene	51289
UniProt	Q9NSD7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NSD7
Antibodypedia	RXFP3 antibodies

PROTEIN BROWSER

RXFP3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RXFP3-001 ENSP00000328708 ENST00000330120	Q9NSD7 [Direct mapping] Relaxin-3 receptor 1 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007218 [neuropeptide signaling pathway] GO:0008528 [G-protein coupled peptide receptor activity] GO:0016021 [integral component of membrane] GO:0032467 [positive regulation of cytokinesis] GO:0051482 [positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway] Show all	469 aa 51.1 kDa	No	7