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Most cancer tissues showed weak to moderate cytoplasmic staining with additional nuclear positivity in many cases. Several lymphomas, gliomas, renal cell carcinomas and hepatocellular carcinomas were negative.
Few cases of lung, liver and breast cancers displayed moderate to strong cytoplasmic staining with additional nuclear positivity in carcinoids. Remaining cancer tissues were weakly stained or negative.
Several cases of liver cancers as well as cases of melanomas, endometrial, ovarian, renal and lung cancers showed moderate cytoplasmic staining. A subset of tumor cells in renal cancers displayed moderate nuclear membranous staining. Remaining cancers were weakly stained or negative.
GENE INFORMATION
Gene name
RGPD6 (HGNC Symbol)
Synonyms
RGP6
Description
RANBP2-like and GRIP domain containing 6 (HGNC Symbol)