Expression of SMDT1 in cancer - Summary

CANCER ATLAS

Gene description

Single-pass membrane protein with aspartate-rich tail 1

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA032117

GENE INFORMATION
Gene name	SMDT1 (HGNC Symbol)
Synonyms	C22orf32, DDDD, dJ186O1.1, EMRE
Description	Single-pass membrane protein with aspartate-rich tail 1 (HGNC Symbol)
Entrez gene summary
Chromosome	22
Cytoband	q13.2
Chromosome location (bp)	42079691 - 42084284
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183172 (version 83.38)
Entrez gene	91689
UniProt	Q9H4I9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H4I9
Antibodypedia	SMDT1 antibodies

PROTEIN BROWSER

SMDT1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SMDT1-001 ENSP00000327467 ENST00000331479	Q9H4I9 [Direct mapping] Essential MCU regulator, mitochondrial Show all	Transporters Accessory Factors Involved in Transport Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006851 [mitochondrial calcium ion transport] GO:0031305 [integral component of mitochondrial inner membrane] GO:0036444 [calcium ion transmembrane import into mitochondrion] GO:0051560 [mitochondrial calcium ion homeostasis] GO:1990246 [uniplex complex] Show all	107 aa 11.4 kDa	No	1