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DAZAP2

GENERAL INFORMATION

Gene name

 DAZAP2

Gene description

 DAZ associated protein 2

Protein class

 Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 8
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 DAZAP2 (HGNC Symbol)

Synonyms

 KIAA0058

Description

 DAZ associated protein 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Chromosome

 12

Cytoband

 q13.13

Chromosome location (bp)

 51238292 - 51271362

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000183283 (version 83.38)

Entrez gene

 9802

UniProt

 Q15038 (UniProt - Evidence at protein level)

neXtProt

 NX_Q15038

Antibodypedia

 DAZAP2 antibodies

PROTEIN BROWSER
DAZAP2-001
DAZAP2-002
DAZAP2-003
DAZAP2-010
DAZAP2-013
DAZAP2-014
DAZAP2-015
DAZAP2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DAZAP2-001
ENSP00000394699
ENST00000412716
Q15038 [Direct mapping]
DAZ-associated protein 2
A0A024R110 [Target identity:100%; Query identity:100%]
DAZ associated protein 2, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0050699 [WW domain binding]
Show all
 168 aa
17.3 kDa 		No 0
DAZAP2-002
ENSP00000448051
ENST00000549555
Q15038 [Direct mapping]
DAZ-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0050699 [WW domain binding]
Show all
 207 aa
22.8 kDa 		No 0
DAZAP2-003
ENSP00000408251
ENST00000425012
Q15038 [Direct mapping]
DAZ-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0050699 [WW domain binding]
Show all
 153 aa
16.2 kDa 		No 0
DAZAP2-010
ENSP00000446554
ENST00000549732
Q15038 [Direct mapping]
DAZ-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0050699 [WW domain binding]
Show all
 136 aa
14 kDa 		No 0
DAZAP2-013
ENSP00000398804
ENST00000439799
Q15038 [Direct mapping]
DAZ-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0050699 [WW domain binding]
Show all
 86 aa
9.2 kDa 		No 0
DAZAP2-014
ENSP00000447842
ENST00000551313
F8VUW5 [Direct mapping]
DAZ-associated protein 2
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 108 aa
10.8 kDa 		Yes 0
DAZAP2-015
ENSP00000474597
ENST00000604900
S4R3Q0 [Direct mapping]
DAZ-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 134 aa
13.9 kDa 		No 0
DAZAP2-201
ENSP00000412812
ENST00000449723
Q15038 [Direct mapping]
DAZ-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0050699 [WW domain binding]
Show all
 146 aa
15.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.