Cell atlas - RIPK4 - The Human Protein Atlas

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RIPK4

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	RIPK4
Gene description	Receptor-interacting serine-threonine kinase 4
Protein class	Disease related genes Enzymes Potential drug targets Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (HaCaT)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HaCaT) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	RIPK4 (HGNC Symbol)
Synonyms	ANKK2, ANKRD3, DIK, PKK, RIP4
Description	Receptor-interacting serine-threonine kinase 4 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008]
Chromosome	21
Cytoband	q22.3
Chromosome location (bp)	41739369 - 41767106
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183421 (version 83.38)
Entrez gene	54101
UniProt	P57078 (UniProt - Evidence at protein level)
neXtProt	NX_P57078
Antibodypedia	RIPK4 antibodies

PROTEIN BROWSER

RIPK4-001	RIPK4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RIPK4-001 ENSP00000332454 ENST00000332512	P57078 [Direct mapping] Receptor-interacting serine/threonine-protein kinase 4 Show all	Enzymes ENZYME proteins Transferases Kinases TKL Ser/Thr protein kinases Predicted intracellular proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002009 [morphogenesis of an epithelium] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] GO:0016020 [membrane] GO:0051092 [positive regulation of NF-kappaB transcription factor activity] Show all	784 aa 86.4 kDa	No	0
RIPK4-201 ENSP00000330161 ENST00000352483	P57078 [Direct mapping] Receptor-interacting serine/threonine-protein kinase 4 Show all	Enzymes ENZYME proteins Transferases Kinases TKL Ser/Thr protein kinases Predicted intracellular proteins Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014) Show all	GO:0002009 [morphogenesis of an epithelium] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] GO:0016020 [membrane] GO:0051092 [positive regulation of NF-kappaB transcription factor activity] Show all	832 aa 91.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.