Cell atlas - GPR132 - The Human Protein Atlas

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GPR132

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	GPR132
Gene description	G protein-coupled receptor 132
Protein class	G-protein coupled receptors Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (HDLM-2, Karpas-707, THP-1)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (HDLM-2, Karpas-707, THP-1) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	GPR132 (HGNC Symbol)
Synonyms	G2A
Description	G protein-coupled receptor 132 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Chromosome	14
Cytoband	q32.33
Chromosome location (bp)	105049389 - 105065445
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183484 (version 83.38)
Entrez gene	29933
UniProt	Q9UNW8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UNW8
Antibodypedia	GPR132 antibodies

PROTEIN BROWSER

GPR132-001	GPR132-002	GPR132-003	GPR132-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR132-001 ENSP00000328818 ENST00000329797	Q9UNW8 [Direct mapping] Probable G-protein coupled receptor 132 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0000082 [G1/S transition of mitotic cell cycle] GO:0004930 [G-protein coupled receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway] GO:0010972 [negative regulation of G2/M transition of mitotic cell cycle] GO:0016021 [integral component of membrane] Show all	380 aa 42.5 kDa	No	7
GPR132-002 ENSP00000376364 ENST00000392585	Q9UNW8 [Direct mapping] Probable G-protein coupled receptor 132 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	371 aa 41.5 kDa	No	7
GPR132-003 ENSP00000438094 ENST00000539291	Q9UNW8 [Direct mapping] Probable G-protein coupled receptor 132 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	380 aa 42.5 kDa	No	7
GPR132-004 ENSP00000448776 ENST00000549990	A0A0G2JL29 [Direct mapping] Probable G-protein-coupled receptor 132 Show all	Predicted intracellular proteins Show all		10 aa 1.2 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.