Cell atlas - FAM46C - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

FAM46C

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	FAM46C
Gene description	Family with sequence similarity 46, member C
Protein class	Cancer-related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Cell line enhanced (Karpas-707, RPMI-8226, U-266/70)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA054049
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (Karpas-707, RPMI-8226, U-266/70) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA054049	MCF7	Nucleoplasm
	HPA054049	RT4	No staining
	HPA054049	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	FAM46C (HGNC Symbol)
Synonyms	FLJ20202
Description	Family with sequence similarity 46, member C (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p12
Chromosome location (bp)	117605934 - 117628372
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183508 (version 83.38)
Entrez gene	54855
UniProt	Q5VWP2 (UniProt - Evidence at protein level)
neXtProt	NX_Q5VWP2
Antibodypedia	FAM46C antibodies

PROTEIN BROWSER

FAM46C-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM46C-001 ENSP00000358458 ENST00000369448	Q5VWP2 [Direct mapping] Protein FAM46C Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Other Mutations COSMIC Missense Mutations COSMIC Frameshift Mutations Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	391 aa 44.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.