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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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PSG9
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

PSG9

Gene description

Pregnancy specific beta-1-glycoprotein 9

Protein class

Plasma proteins
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

8
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (placenta)
GTEx:Not detected
FANTOM5:Tissue enriched (placenta)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in trophoblasts.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.

Reliability score

Approved based on 1 antibody.
HPA046327
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (placenta)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (placenta)

GENE INFORMATION

Gene name

PSG9 (HGNC Symbol)

Synonyms

PSG11, PSGII

Description

Pregnancy specific beta-1-glycoprotein 9 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the pregnancy-specific glycoprotein (PSG) family. This protein family and the closely related carcinoembryonic antigen cell adhesion molecule (CEACAM) gene family are both members of the immunoglobulin superfamily, and are organized as a large gene cluster. This protein is thought to inhibit platelet-fibrinogen interactions. Several studies suggest that reduced serum concentrations of PSGs are associated with fetal growth restrictions, while up-regulation of this gene has been observed in colorectal cancers. Several pseudogenes of this gene are found on chromosome 19. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms. [provided by RefSeq, Sep 2014]

Chromosome

19

Cytoband

q13.31

Chromosome location (bp)

43211791 - 43269530

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183668 (version 83.38)

Entrez gene

5678

UniProt

Q00887 (UniProt - Evidence at transcript level)

neXtProt

NX_Q00887

Antibodypedia

PSG9 antibodies

PROTEIN BROWSER

PSG9-001
PSG9-002
PSG9-006
PSG9-007
PSG9-008
PSG9-009
PSG9-011
PSG9-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSG9-001
ENSP00000270077
ENST00000270077
Q00887 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 9
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0007565 [female pregnancy]
Show all
426 aa
48.3 kDa
Yes 0
PSG9-002
ENSP00000244293
ENST00000244293
Q00887 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0007565 [female pregnancy]
Show all
402 aa
45.3 kDa
Yes 1
PSG9-006
ENSP00000471174
ENST00000596730
M0R0E4 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 9
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
309 aa
34.8 kDa
Yes 1
PSG9-007
ENSP00000396753
ENST00000443718
E7EW65 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 9
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
333 aa
37.7 kDa
Yes 0
PSG9-008
ENSP00000471453
ENST00000593948
M0R0U8 [Direct mapping]
Pregnancy specific beta-1-glycoprotein 9, isoform CRA_c; Pregnancy-specific beta-1-glycoprotein 9
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
333 aa
37.6 kDa
Yes 0
PSG9-009
ENSP00000291752
ENST00000291752
G3XAA7 [Direct mapping]
Pregnancy specific beta-1-glycoprotein 9, isoform CRA_d; Pregnancy-specific beta-1-glycoprotein 9
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
240 aa
27.1 kDa
Yes 0
PSG9-011
ENSP00000400484
ENST00000418820
H7C1I4 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 9
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
326 aa
37.1 kDa
Yes 0
PSG9-201
ENSP00000481887
ENST00000621109
A0A087WYK1 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 9
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
419 aa
47.7 kDa
Yes 0

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