Tissue expression of BMP8A - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	BMP8A
Gene description	Bone morphogenetic protein 8a
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (thyroid gland)
GTEx:	Tissue enhanced (thyroid gland)
FANTOM5:	Tissue enhanced (thyroid gland)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (thyroid gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland)

GENE INFORMATION
Gene name	BMP8A
Synonyms
Description	Bone morphogenetic protein 8a (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the transforming growth factor beta superfamily of regulatory proteins. The encoded preproprotein undergoes proteolytic processing to generate the mature protein. Studies in laboratory mice suggest that this protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Nov 2015]
Chromosome	1
Cytoband	p34.3
Chromosome location (bp)	39491646 - 39525935
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000183682 (version 83.38)
Entrez gene	353500
UniProt	Q7Z5Y6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7Z5Y6
Antibodypedia	BMP8A antibodies

PROTEIN BROWSER

BMP8A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BMP8A-001 ENSP00000327440 ENST00000331593	Q7Z5Y6 [Direct mapping] Bone morphogenetic protein 8A Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0001503 [ossification] GO:0002024 [diet induced thermogenesis] GO:0005125 [cytokine activity] GO:0005160 [transforming growth factor beta receptor binding] GO:0005615 [extracellular space] GO:0008083 [growth factor activity] GO:0010862 [positive regulation of pathway-restricted SMAD protein phosphorylation] GO:0030509 [BMP signaling pathway] GO:0040007 [growth] GO:0042981 [regulation of apoptotic process] GO:0043408 [regulation of MAPK cascade] GO:0046676 [negative regulation of insulin secretion] GO:0048468 [cell development] GO:0051216 [cartilage development] GO:0060395 [SMAD protein signal transduction] GO:0070700 [BMP receptor binding] GO:2000505 [regulation of energy homeostasis] Show all	402 aa 44.8 kDa	Yes	0