Expression of MRGPRX2 in cancer - Summary

CANCER ATLAS

Gene description

MAS-related GPR, member X2

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA055220

GENE INFORMATION
Gene name	MRGPRX2 (HGNC Symbol)
Synonyms	MRGX2
Description	MAS-related GPR, member X2 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	p15.1
Chromosome location (bp)	19054455 - 19060681
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183695 (version 83.38)
Entrez gene	117194
UniProt	Q96LB1 (UniProt - Evidence at protein level)
neXtProt	NX_Q96LB1
Antibodypedia	MRGPRX2 antibodies

PROTEIN BROWSER

MRGPRX2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MRGPRX2-001 ENSP00000333800 ENST00000329773	Q96LB1 [Direct mapping] Mas-related G-protein coupled receptor member X2 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0030431 [sleep] GO:0032467 [positive regulation of cytokinesis] GO:0042629 [mast cell granule] GO:0042923 [neuropeptide binding] GO:0043303 [mast cell degranulation] GO:0045576 [mast cell activation] GO:1990595 [mast cell secretagogue receptor activity] Show all	330 aa 37.1 kDa	No	7