Expression of CNGA2 in cancer - Summary

CANCER ATLAS

Gene description

Cyclic nucleotide gated channel alpha 2

Protein class

Predicted membrane proteins, Voltage-gated ion channels

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA015065

GENE INFORMATION
Gene name	CNGA2 (HGNC Symbol)
Synonyms	CNCA, CNCA1, CNG2, FLJ46312, OCNC1, OCNCa, OCNCALPHA
Description	Cyclic nucleotide gated channel alpha 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. [provided by RefSeq, Jan 2010]
Chromosome	X
Cytoband	q28
Chromosome location (bp)	151738451 - 151745304
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183862 (version 83.38)
Entrez gene	1260
UniProt	Q16280 (UniProt - Evidence at transcript level)
neXtProt	NX_Q16280
Antibodypedia	CNGA2 antibodies

PROTEIN BROWSER

CNGA2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CNGA2-001 ENSP00000328478 ENST00000329903	Q16280 [Direct mapping] Cyclic nucleotide-gated olfactory channel Show all	Voltage-gated ion channels Cyclic Nucleotide-Regulated Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005216 [ion channel activity] GO:0005222 [intracellular cAMP activated cation channel activity] GO:0005223 [intracellular cGMP activated cation channel activity] GO:0005249 [voltage-gated potassium channel activity] GO:0005516 [calmodulin binding] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006996 [organelle organization] GO:0007608 [sensory perception of smell] GO:0016020 [membrane] GO:0030552 [cAMP binding] GO:0030553 [cGMP binding] GO:0030660 [Golgi-associated vesicle membrane] GO:0042391 [regulation of membrane potential] GO:0050896 [response to stimulus] GO:0055085 [transmembrane transport] GO:0060170 [ciliary membrane] GO:0071805 [potassium ion transmembrane transport] Show all	664 aa 76 kDa	No	5