Cell atlas - KCNH8 - The Human Protein Atlas

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KCNH8

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	KCNH8
Gene description	Potassium channel, voltage gated eag related subfamily H, member 8
Protein class	Predicted membrane proteins Voltage-gated ion channels
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (SH-SY5Y)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (SH-SY5Y) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	KCNH8 (HGNC Symbol)
Synonyms	elk3, Kv12.1
Description	Potassium channel, voltage gated eag related subfamily H, member 8 (HGNC Symbol)
Entrez gene summary	Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. [provided by RefSeq, Jul 2008]
Chromosome	3
Cytoband	p24.3
Chromosome location (bp)	19148454 - 19535646
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000183960 (version 83.38)
Entrez gene	131096
UniProt	Q96L42 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96L42
Antibodypedia	KCNH8 antibodies

PROTEIN BROWSER

KCNH8-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KCNH8-001 ENSP00000328813 ENST00000328405	Q96L42 [Direct mapping] Potassium voltage-gated channel subfamily H member 8 Show all	Voltage-gated ion channels Voltage-Gated Potassium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0000155 [phosphorelay sensor kinase activity] GO:0000160 [phosphorelay signal transduction system] GO:0005216 [ion channel activity] GO:0005249 [voltage-gated potassium channel activity] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0007268 [synaptic transmission] GO:0016020 [membrane] GO:0023014 [signal transduction by protein phosphorylation] GO:0034765 [regulation of ion transmembrane transport] GO:0042391 [regulation of membrane potential] GO:0055085 [transmembrane transport] GO:0071805 [potassium ion transmembrane transport] Show all	1107 aa 123.8 kDa	No	6

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.