Expression of OR2T10 in cancer - Summary

CANCER ATLAS

Gene description

Olfactory receptor, family 2, subfamily T, member 10

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA052019

GENE INFORMATION
Gene name	OR2T10
Synonyms
Description	Olfactory receptor, family 2, subfamily T, member 10 (HGNC Symbol)
Entrez gene summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	q44
Chromosome location (bp)	248592830 - 248593768
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000184022 (version 83.38)
Entrez gene	127069
UniProt	Q8NGZ9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NGZ9
Antibodypedia	OR2T10 antibodies

PROTEIN BROWSER

OR2T10-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OR2T10-001 ENSP00000329210 ENST00000330500	Q8NGZ9 [Direct mapping] Olfactory receptor 2T10 Show all	G-protein coupled receptors Odorant/olfactory and gustatory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004984 [olfactory receptor activity] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007608 [sensory perception of smell] GO:0016021 [integral component of membrane] GO:0050911 [detection of chemical stimulus involved in sensory perception of smell] Show all	312 aa 35.4 kDa	No	7