Cell atlas - FAM120C - The Human Protein Atlas

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FAM120C

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear speckles

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	FAM120C
Gene description	Family with sequence similarity 120C
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nuclear speckles.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear speckles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA047677
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nuclear speckles.

Main location

Nuclear speckles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA047677	HEK 293	Nuclear speckles
	HPA047677	PC-3	Nuclear speckles
	HPA047677	PC-3	Cytosol
	HPA047677	U-2 OS	Nuclear speckles

GENE INFORMATION
Gene name	FAM120C (HGNC Symbol)
Synonyms	CXorf17, FLJ20506, ORF34
Description	Family with sequence similarity 120C (HGNC Symbol)
Entrez gene summary	This gene encodes a potential transmembrane protein and lies in a region where mutations and deletions have been associated with intellectual disability and autism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Chromosome	X
Cytoband	p11.22
Chromosome location (bp)	54068324 - 54183281
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184083 (version 83.38)
Entrez gene	54954
UniProt	Q9NX05 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NX05
Antibodypedia	FAM120C antibodies

PROTEIN BROWSER

FAM120C-001	FAM120C-003	FAM120C-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM120C-001 ENSP00000364324 ENST00000375180	Q9NX05 [Direct mapping] Constitutive coactivator of PPAR-gamma-like protein 2 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0044822 [poly(A) RNA binding] Show all	1096 aa 120.6 kDa	No	0
FAM120C-003 ENSP00000329896 ENST00000328235	F8W881 [Direct mapping] Constitutive coactivator of PPAR-gamma-like protein 2 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		895 aa 99.4 kDa	No	0
FAM120C-004 ENSP00000420718 ENST00000477084	Q9NX05 [Direct mapping] Constitutive coactivator of PPAR-gamma-like protein 2 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0044822 [poly(A) RNA binding] Show all	238 aa 25.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.