Cell atlas - CDR1 - The Human Protein Atlas

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CDR1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Centrosome
	Golgi apparatus
	Nucleoplasm

Human cell
	Centrosome
	Golgi Apparatus
	Nucleoplasm

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GENERAL INFORMATION
Gene name	CDR1
Gene description	Cerebellar degeneration-related protein 1, 34kDa
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the Golgi apparatus, centrosome & nucleoplasm.
RNA cell category	Cell line enhanced (U-87 MG, ASC TERT1)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved), Golgi apparatus (approved), Centrosome (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA073147
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-87 MG, ASC TERT1) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the Golgi apparatus, centrosome & nucleoplasm.

Main location

Nucleoplasm (approved), Golgi apparatus (approved), Centrosome (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA073147	BJ	Nucleoplasm
			Golgi apparatus
			Centrosome
	HPA073147	SH-SY5Y	Nucleoplasm
			Golgi apparatus
			Centrosome
	HPA073147	U-2 OS	Nucleoplasm
			Golgi apparatus
			Centrosome

GENE INFORMATION
Gene name	CDR1 (HGNC Symbol)
Synonyms	CDR, CDR34, CDR62A
Description	Cerebellar degeneration-related protein 1, 34kDa (HGNC Symbol)
Entrez gene summary	Autoantibodies directed against the protein encoded by this intronless gene have been found in some patients with paraneoplastic cerebellar degeneration. The encoded protein contains several hexapeptide repeats. [provided by RefSeq, Jan 2010]
Chromosome	X
Cytoband	q27.1
Chromosome location (bp)	140782405 - 140784871
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184258 (version 83.38)
Entrez gene	1038
UniProt	P51861 (UniProt - Evidence at protein level)
neXtProt	NX_P51861
Antibodypedia	CDR1 antibodies

PROTEIN BROWSER

CDR1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDR1-001 ENSP00000359563 ENST00000370532	P51861 [Direct mapping] Cerebellar degeneration-related antigen 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	262 aa 31.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.