Tissue expression of LPAR5 - Summary - The Human Protein Atlas

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LPAR5

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	LPAR5
Gene description	Lysophosphatidic acid receptor 5
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Tissue enhanced (esophagus)
FANTOM5:	Tissue enhanced (tonsil)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA013170
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (esophagus)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (tonsil)

GENE INFORMATION
Gene name	LPAR5 (HGNC Symbol)
Synonyms	GPR92, GPR93, KPG_010, LPA5
Description	Lysophosphatidic acid receptor 5 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008]
Chromosome	12
Cytoband	p13.31
Chromosome location (bp)	6618835 - 6636447
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184574 (version 83.38)
Entrez gene	57121
UniProt	Q9H1C0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H1C0
Antibodypedia	LPAR5 antibodies

PROTEIN BROWSER

LPAR5-001	LPAR5-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LPAR5-001 ENSP00000327875 ENST00000329858	Q9H1C0 [Direct mapping] Lysophosphatidic acid receptor 5 Q5KU18 [Target identity:100%; Query identity:100%] G protein-coupled receptor 92, isoform CRA_a; G-protein coupled receptor; Lysophosphatidic acid receptor 5; cDNA, FLJ93614, Homo sapiens G protein-coupled receptor 92 (GPR92), mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Lysolipids receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003674 [molecular_function] GO:0004930 [G-protein coupled receptor activity] GO:0005575 [cellular_component] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	372 aa 41.3 kDa	No	7
LPAR5-201 ENSP00000393098 ENST00000431922	Q9H1C0 [Direct mapping] Lysophosphatidic acid receptor 5 Q5KU18 [Target identity:100%; Query identity:100%] G protein-coupled receptor 92, isoform CRA_a; G-protein coupled receptor; Lysophosphatidic acid receptor 5; cDNA, FLJ93614, Homo sapiens G protein-coupled receptor 92 (GPR92), mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Lysolipids receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003674 [molecular_function] GO:0004930 [G-protein coupled receptor activity] GO:0005575 [cellular_component] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	372 aa 41.3 kDa	No	7

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.