Tissue expression of CDCA2 - Summary - The Human Protein Atlas

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CDCA2

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CDCA2
Gene description	Cell division cycle associated 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enhanced (testis, appendix)

Protein evidence

Evidence at protein level

Protein expression

General nuclear membrane expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. External characterization data supports antibody staining.
Reliability score	Approved based on 2 antibodies. HPA026293 , HPA030049
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis, appendix)

GENE INFORMATION
Gene name	CDCA2 (HGNC Symbol)
Synonyms	PPP1R81, Repo-Man
Description	Cell division cycle associated 2 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	p21.2
Chromosome location (bp)	25458997 - 25507920
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184661 (version 83.38)
Entrez gene	157313
UniProt	Q69YH5 (UniProt - Evidence at protein level)
neXtProt	NX_Q69YH5
Antibodypedia	CDCA2 antibodies

PROTEIN BROWSER

CDCA2-001	CDCA2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDCA2-001 ENSP00000328228 ENST00000330560	Q69YH5 [Direct mapping] Cell division cycle-associated protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005694 [chromosome] GO:0005737 [cytoplasm] GO:0007059 [chromosome segregation] GO:0007067 [mitotic nuclear division] GO:0035307 [positive regulation of protein dephosphorylation] GO:0051301 [cell division] Show all	1023 aa 112.7 kDa	No	0
CDCA2-002 ENSP00000370040 ENST00000380665	E9PEI0 [Direct mapping] Cell division cycle-associated protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] Show all	1008 aa 111 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.